Thiophenol → HCID 22842163, compound

Participants

Reaction Steps

A solution of (2) (27.5 g) in EtOH (46 ml) was added dropwise during 10 min to a solution of PhSNa prepared from PhSH (11.2 ml) and Na (3.01 g) in EtOH (130 ml) with stirring at room temperature. The mixture was stirred and heated under reflux for 2.5 hr. The mixture was poured into iced 2N aqueous NaOH and extracted with ether. The ether solution was washed with brine, dried over MgSO4 and concentrated in vacuo to give 22.3 g of (3).

Provenance & Evidence