Octanoic acid, 6-oxo-, methyl ester → 1-(4-Chlorobenzyl)-3-methyl-5-methoxy-2-(4'-carboxybutyl)indole

HRID 1090187Notes

Reaction equation

HRID 1090187 reaction equation
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][N:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)N)=[CH:5][CH:4]=1.O=[C:21]([CH2:30][CH3:31])[CH2:22][CH2:23][CH2:24][CH2:25][C:26]([O:28]C)=[O:27]>CO>[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][N:10]2[C:12]3[C:17](=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=3)[C:30]([CH3:31])=[C:21]2[CH2:22][CH2:23][CH2:24][CH2:25][C:26]([OH:28])=[O:27])=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 11309799Octanoic acid, 6-oxo-, methyl esterHCID 189475691-(4-Chlorobenzyl)-1-(4-methoxyphenyl)hydrazine hydrochloride

Product 1

HCID 156787631-(4-Chlorobenzyl)-3-methyl-5-methoxy-2-(4'-carboxybutyl)indole

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Following the procedure of Example 2, but using 1-[(4-chlorophenyl)methyl]-1-(4-methoxyphenyl)-hydrazine hydrochloride and methyl 6-oxooctanoate as the starting materials and methanol as the solvent, the title compound was prepared.

Sources & evidence

ORD record
ord-b676bffaf3134365886776f065c938bb
Source dataset
uspto-grants-1992_01
Patent number
US05081145

Reaction notes

Loading…