HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2,2-dimethyl-4-oxohexanoate → 3-[1-(4-Bromobenzyl)-3-methyl-5-methoxyindol-2-yl]-2,2-dimethylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2,2-dimethyl-4-oxohexanoate | HCID 13164740 | — |
| Reactant | N-(p-Bromobenzyl)-N-(4-methoxyphenyl)hydrazine hydrochloride | HCID 19041688 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | 3-[1-(4-Bromobenzyl)-3-methyl-5-methoxyindol-2-yl]-2,2-dimethylpropanoic acid | HCID 15678789 | — |
Reaction Steps
Following the method of Example 2, but using 1-[4-bromobenzyl]-1-(4-methoxy phenyl) hydrazine hydrochloride and methyl-2,2-dimethyl-4-oxohexanoate as the starting materials, using t-butanol as the solvent, the title compound was prepared.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081145 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-a91db37bab0846ad9dd634a0efa0de15 |
| Source note | uspto-grants-1992_01 |