反应详情

500 mg of the product of Step 1 was dissolved in 35 ml of absolute ethanol and 50 mg of 10% palladium on carbon catalyst added. The suspension was hydrogenated at 50 psi until consumption of 2 mole equivalents of hydrogen occurred. The catalyst was removed by filtration and the title compound was isolated by vacuum distilation of the solvent (489 mg).

1. customThe suspension was hydrogenated at 50 psi until consumption of 2 mole equivalents of hydrogen
2. customThe catalyst was removed by filtration