Ethanol → HCID 178448832, compound

HRID 1090231Notes

Reaction equation

HRID 1090231 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH:7]([CH3:11])[CH2:8][CH2:9][NH2:10])=[CH:3][CH:2]=1.[N:12]1[C:20]2[C:15]3[C:16](=[CH:21][CH:22]=[CH:23][C:14]=3[C:13]=1S)[CH:17]=[CH:18][CH:19]=2.C(O)C.C(Cl)(Cl)Cl>ClCCl>[N:1]1[CH:6]=[CH:5][C:4]([CH:7]([CH3:11])[CH2:8][CH2:9][NH:10][C:13]2[C:14]3[CH:23]=[CH:22][CH:21]=[C:16]4[C:15]=3[C:20](=[CH:19][CH:18]=[CH:17]4)[N:12]=2)=[CH:3][CH:2]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 6212ChloroformHCID 147508173-(Pyridin-4-yl)butan-1-amineHCID 178527764HCID 178527764, compound

Product 1

HCID 178448832HCID 178448832, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared by the procedure of Example 55, utilizing 3.1 grams of 3-(4-pyridinyl)butanamine, 3.9 grams of benz(cd)indol-2-thiol, 6.4 grams of mercuric acetate, and 300 ml of ethanol. Chloroform (200 ml) was utilized as the partitioning solvent in place of dichloromethane. When the chloroform was being removed in vacuo, crystallization of the title compound suddenly occurred. The precipitate was collected, washed with a little chloroform, and dried. The yield was 3.9 grams; mp 220° C.-221° C. with decomposition.

Workup

  1. customWhen the chloroform was being removed in vacuo, crystallization of the title compound
  2. customThe precipitate was collected
  3. washwashed with a little chloroform
  4. customdried

Sources & evidence

ORD record
ord-93a06e6c415f427bb7b5418293efe56d
Source dataset
uspto-grants-1992_01
Patent number
US05081131

Reaction notes

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