4-(Pyridin-4-yl)butan-1-amine → HCID 178506530, compound

HRID 1090238Notes

Reaction equation

HRID 1090238 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])=[CH:3][CH:2]=1.[IH:12].CS[C:15]1[C:23]2[CH:24]=[CH:25][CH:26]=[C:21]3[C:22]=2[C:17](=[CH:18][CH:19]=[CH:20]3)[N:16]=1>C(O)C>[IH:12].[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:15]2[C:23]3[CH:24]=[CH:25][CH:26]=[C:21]4[C:22]=3[C:17](=[CH:18][CH:19]=[CH:20]4)[N:16]=2)=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 135575324-(Pyridin-4-yl)butan-1-amineHCID 201506502-Methylthiobenz(cd)indole hydriodide

Product 1

HCID 178506530HCID 178506530, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture consisting of 3.3 grams of 4-(4-pyridinyl)butanamine, 6.5 grams of 2-methylthiobenz (cd)indole hydriodide, and 200 ml of ethanol. Cooling to room temperature failed to effect precipitation, so that solution was concentrated to 100 ml volume and cooled at -10° C. The precipitate that formed was collected, washed with ethanol, and dried. The yield of title compound was 6.1 grams; mp 197° C.-199° C. with decomposition.

Workup

  1. customprecipitation
  2. concentrationso that solution was concentrated to 100 ml volume
  3. temperaturecooled at -10° C
  4. customThe precipitate that formed
  5. customwas collected
  6. washwashed with ethanol
  7. customdried

Sources & evidence

ORD record
ord-f374b10a4ae94df5bfe03d071d487a06
Source dataset
uspto-grants-1992_01
Patent number
US05081131

Reaction notes

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