HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 178525523, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-(2-Aminoethoxy)pyridine | HCID 96890 | — |
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | 2-Methylthiobenz(cd)indole hydriodide | HCID 20150650 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 178525523 | HCID 178525523 | — |
Reaction Steps
A mixture consisting of 3.0 grams of 2-(2-pyridinyloxy) ethylamine, 6.5 grams of 2-methylthiobenz(cd)indole hydriodide, and 150 ml of ethanol was stirred and heated under reflux, utilizing the conditions of Example 16. The crude free base (weight, 7.1 grams) was dissolved in 20 ml of acetone and added to a stirred boiling solution of 5.5 grams of fumaric acid in 1200 ml of acetone. After cooling the precipitate of the title compound was collected, washed with acetone, and dried; yield, 7.6 grams; mp 184° C.-185° C. with decomposition.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081131 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-946965078e15461fb924080b3ca468db |
| Source note | uspto-grants-1992_01 |