反应详情

A mixture consisting of 2.8 grams of 3-(1H-pyrazol-1-yl)propanamine, 3.7 grams of benz(cd)indol-2-thiol, 7.0 grams of mercuric acetate, and 400 ml of ethanol was stirred and heated under reflux, by the conditions of Example 55. The isolated crude free base, weight 4.0 grams, was dissolved in 150 ml of acetone and added to stirred boiling solution of 3.5 grams of fumaric acid in 800 ml of acetone. After cooling, the precipitate of the title compound was collected, washed with acetone, and dried. The yield was 4.1 grams; mp 178° C.-180° C. was decomposition.

1. temperatureheated
2. temperatureunder reflux, by the conditions of Example 55
3. customThe isolated crude free base, weight 4.0 grams
4. additionadded
5. stirringto stirred
6. temperatureAfter cooling
7. customthe precipitate of the title compound was collected
8. washwashed with acetone
9. customdried