3-(5-(2-Biphenylyl)-1,3,4-thiadiazol-2-yl)propanamine → HCID 178420079, compound

HRID 1090256Notes

Reaction equation

HRID 1090256 reaction equation
[C:1]1([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[S:11][C:10]([CH2:12][CH2:13][CH2:14][NH2:15])=[N:9][N:8]=1.I.CS[C:25]1[C:33]2[CH:34]=[CH:35][CH:36]=[C:31]3[C:32]=2[C:27](=[CH:28][CH:29]=[CH:30]3)[N:26]=1>C(O)C>[C:1]1([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[S:11][C:10]([CH2:12][CH2:13][CH2:14][NH:15][C:25]2[C:33]3[CH:34]=[CH:35][CH:36]=[C:31]4[C:32]=3[C:27](=[CH:28][CH:29]=[CH:30]4)[N:26]=2)=[N:9][N:8]=1

Participants

4

Reactant 2

HCID 136841473-(5-(2-Biphenylyl)-1,3,4-thiadiazol-2-yl)propanamineHCID 201506502-Methylthiobenz(cd)indole hydriodide

Product 1

HCID 178420079HCID 178420079, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 3-(5-(2-biphenylyl)-1,3,4-thiadiazol-2-yl)propanamine in ethanol is treated with 2-methylthiobenz(cd)indole hydriodide by the conditions of Example 52. Neutralization yields the title compound.

Sources & evidence

ORD record
ord-ab6094c1411b4cee971df69baa28e82c
Source dataset
uspto-grants-1992_01
Patent number
US05081131

Reaction notes

Loading…