HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2,2-dimethyl-5-methylthio-4-oxopentanoate → 1(p-Chlorobenzyl)-alpha,alpha-dimethyl-3-methylthio-5-(iso-propyl)-indole-2-propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2,2-dimethyl-5-methylthio-4-oxopentanoate | HCID 15035406 | — |
| Reactant | 1-(4-Chlorobenzyl)-1-[4-(isopropyl)phenyl]hydrazine, Hydrochloride | HCID 19752394 | — |
| Product | 1(p-Chlorobenzyl)-alpha,alpha-dimethyl-3-methylthio-5-(iso-propyl)-indole-2-propanoic acid | HCID 15035388 | — |
Reaction Steps
Following the procedure of Example 10, but using 1-(p-chlorobenzyl)-1-[4-(i-propyl)phenyl]hydrazine hydrochloride and methyl 2,2-dimethyl-5-methylthio-4-oxopentanoate as starting materials and hydrolysis at reflux, the title compound was prepared, mp 143°-144°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081138 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-dfe071d605c649599a1ba9c374d3a855 |
| Source note | uspto-grants-1992_01 |