2-(2,5-Dichloropyrimidin-4-ylamino)-N-methylbenzamide → 2-[5-Chloro-2-(1-methoxy-7-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-ylamino)-pyrimidin-4-ylamino]-N-methyl-benzamide

HRID 109028Notes

Reaction equation

HRID 109028 reaction equation
[Cl:16][c:17]1[n:18][cH:19][c:20]([Cl:34])[c:21]([NH:23][c:24]2[c:25]([C:26](=[O:27])[NH:28][CH3:29])[cH:30][cH:31][cH:32][cH:33]2)[n:22]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([c:13]1[O:14][CH3:15])[CH2:7][CH2:8][C:9](=[O:12])[CH2:10][CH2:11]2>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([c:13]1[O:14][CH3:15])[CH2:7][CH2:8][C:9](=[O:12])[CH2:10][CH2:11]2)[c:17]1[n:18][cH:19][c:20]([Cl:34])[c:21]([NH:23][c:24]2[c:25]([C:26](=[O:27])[NH:28][CH3:29])[cH:30][cH:31][cH:32][cH:33]2)[n:22]1

Participants

3

Reactant 2

HCID 579741322-(2,5-Dichloropyrimidin-4-ylamino)-N-methylbenzamideHCID 672634842-Amino-1-methoxy-5,6,8,9-tetrahydrobenzocyclohepten-7-one

Product 1

HCID 672644932-[5-Chloro-2-(1-methoxy-7-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-ylamino)-pyrimidin-4-ylamino]-N-methyl-benzamide

Sources & evidence

ORD record
ord-6a81f1bff6024819a8f68bf98ca44f10
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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