Ammonia → HCID 19915074, compound

HRID 1090301Notes

Reaction equation

HRID 1090301 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[N:6]=[C:5]([O:11][C:12]2[CH:20]=[CH:19][CH:18]=[C:17]([O:21][C:22]3[N:27]=[C:26]([O:28][CH3:29])[CH:25]=[C:24]([O:30][CH3:31])[N:23]=3)[C:13]=2[C:14]([OH:16])=[O:15])[N:4]=1.[NH3:32]>C1COCC1.C(O)C>[CH3:29][O:28][C:26]1[CH:25]=[C:24]([O:30][CH3:31])[N:23]=[C:22]([O:21][C:17]2[CH:18]=[CH:19][CH:20]=[C:12]([O:11][C:5]3[N:4]=[C:3]([O:2][CH3:1])[CH:8]=[C:7]([O:9][CH3:10])[N:6]=3)[C:13]=2[C:14]([O-:16])=[O:15])[N:27]=1.[NH4+:32]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 443031Bispyribac

Product 1

HCID 19915074HCID 19915074, compoundYield 69.8%

Reagents, catalysts & solvents 1

HCID 21873804Tetrahydrofuran ethanolSolvent

Procedure

2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid (5.1 g) and 28% aqueous ammonia (1.7 g) were mixed with a solvent mixture of THF/ethanol. Precipitated crystals were washed with acetone to obtain the above .drentified compound as white crystals (3.7 g). (Melting point: 135-140° C.

Workup

  1. customPrecipitated crystals
  2. washwere washed with acetone

Sources & evidence

ORD record
ord-54562db4247f43ebac104812ab979e5c
Source dataset
uspto-grants-1992_01
Patent number
US05081244

Reaction notes

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