HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 15599411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 6-(3,4-Dihydro-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one | HCID 15599410 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15599411 | HCID 15599411 | 61% |
Reaction Steps
6-(3,4-Dihydro-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one was suspended in tetrahydrofuran and one equivalent of acetyl chloride was added. After one half hour at 0° C., the solvent was removed in vacuo, and the product was crystallized from ethanol in 61% yield, mp 185.5°-186° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081242 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-d05e59fdc6ef4f1996e38c642983d323 |
| Source note | uspto-grants-1992_01 |