Thionyl Chloride → HCID 14770839, compound

HRID 1090375Notes

Reaction equation

HRID 1090375 reaction equation
[ClH:1].[F:2][C:3]1[CH:11]=[C:10]([CH:12]2[CH2:17][CH2:16][N:15]([CH3:18])[CH2:14][CH2:13]2)[C:9]([F:19])=[CH:8][C:4]=1[C:5](O)=[O:6].S(Cl)([Cl:22])=O>>[ClH:22].[F:2][C:3]1[CH:11]=[C:10]([CH:12]2[CH2:17][CH2:16][N:15]([CH3:18])[CH2:14][CH2:13]2)[C:9]([F:19])=[CH:8][C:4]=1[C:5]([Cl:1])=[O:6]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 67916303HCID 67916303, compound

Product 1

HCID 14770839HCID 14770839, compound

Procedure

2.91 g (10 mmoles) of 2,5-difluoro-4-(1-methyl-4-piperidinyl)benzoic acid hydrochloride was refluxed with thionyl chloride and evaporated to afford the title compound.

Workup

  1. customevaporated

Sources & evidence

ORD record
ord-3a0e54e74b9e4ce08d99f842d4901628
Source dataset
uspto-grants-1992_01
Patent number
US05081254

Reaction notes

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