HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14770825, compound → HCID 54398273, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14770825 | HCID 14770825 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Solvent | Ethyl orthoformate | HCID 31214 | — |
| Product | HCID 54398273 | HCID 54398273 | — |
Reaction Steps
A solution of 2.68 g (7.57 mmol) ethyl 4-(1-acetyl-4-piperidinyl)-2,5-difluoro-β-oxobenzenepropionate in 16 ml of acetic anhydride and 1.9 ml of triethyl orthoformate was refluxed 1.25 hours. The title compound was isolated as a syrup after evaporation under vacuum in an oil bath at 80° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081254 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-c4e489327f084ed6a8e1e8a9003c8b55 |
| Source note | uspto-grants-1992_01 |