HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14770868, compound → HCID 53647345, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14770868 | HCID 14770868 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Solvent | Ethyl orthoformate | HCID 31214 | — |
| Product | HCID 53647345 | HCID 53647345 | — |
Reaction Steps
A solution of 3.95 g (11.25 mmol) ethyl 4-(1-acetyl-1,2,3,6-tetrahydro-4-pyridyl)-2,5-difluoro-β-oxobenzenepropionate in 25 ml of acetic anhydride and 2.8 ml of trietyl orthoformate was refluxed 1.5 hours. The title compound was isolated as a syrup after evaporation under vacuum in an oil bath at 80° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05081254 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-1926c6bf5f554bb29ecfab69d4209a8c |
| Source note | uspto-grants-1992_01 |