HRID1090570

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6328

Methyl iodide

CH3I

结构：CC(=O)OC1CCN(CC(Cc2ccc(OS(=O)(=O)c3cccc4cnccc34)cc2)NS(=O)(=O)c2cccc3cnccc23)CC1

HCID131717151

未命名化合物

PRODUCTS

生成物

结构：CN(C(Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)CN1CCC(O)CC1)S(=O)(=O)c1cccc2cnccc12

HCID19796382

未命名化合物

PROCEDURE

实验过程

The amorphous compound obtained in Example 103 was treated with methyl iodide according to the procedure in Example 89 and the intermediate product was subjected to alkaline hydrolysis according to the procedure in Example 104, to obtain the same product as in Example 99.

WORKUP

后处理

customthe intermediate product was subjected to alkaline hydrolysis
customto obtain the same product as in Example 99

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3d153810520243ec8e9f397d0d8f7124
来源数据集: uspto-grants-1992_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05081246
来源说明: uspto-grants-1992_01

反应 SMILES

C([O:4][CH:5]1[CH2:10][CH2:9][N:8]([CH2:11][CH:12]([NH:34][S:35]([C:38]2[C:39]3[CH:40]=[CH:41][N:42]=[CH:43][C:44]=3[CH:45]=[CH:46][CH:47]=2)(=[O:37])=[O:36])[CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][S:21]([C:24]3[C:25]4[CH:26]=[CH:27][N:28]=[CH:29][C:30]=4[CH:31]=[CH:32][CH:33]=3)(=[O:23])=[O:22])=[CH:16][CH:15]=2)[CH2:7][CH2:6]1)(=O)C.[CH3:48]I>>[OH:4][CH:5]1[CH2:6][CH2:7][N:8]([CH2:11][CH:12]([N:34]([CH3:48])[S:35]([C:38]2[C:39]3[CH:40]=[CH:41][N:42]=[CH:43][C:44]=3[CH:45]=[CH:46][CH:47]=2)(=[O:37])=[O:36])[CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][S:21]([C:24]3[C:25]4[CH:26]=[CH:27][N:28]=[CH:29][C:30]=4[CH:31]=[CH:32][CH:33]=3)(=[O:22])=[O:23])=[CH:16][CH:15]=2)[CH2:9][CH2:10]1