Dichloromethane → Diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzylamino)methylphosphonate

HRID 109060Notes

Reaction equation

HRID 109060 reaction equation
[CH3:1][C:2]([O:3][C:4](=[O:5])[NH:8][c:9]1[c:10]([NH:20][C:21](=[O:22])[c:23]2[cH:24][cH:25][c:26]([CH2:29][NH:30][CH2:31][P:32]([O:33][CH2:34][CH3:35])([O:36][CH2:37][CH3:38])=[O:39])[cH:27][cH:28]2)[cH:11][c:12](-[c:15]2[s:16][cH:17][cH:18][cH:19]2)[cH:13][cH:14]1)([CH3:6])[CH3:7].[Cl:40][CH2:41][Cl:42]>>[NH2:8][c:9]1[c:10]([NH:20][C:21](=[O:22])[c:23]2[cH:24][cH:25][c:26]([CH2:29][NH:30][CH2:31][P:32]([O:33][CH2:34][CH3:35])([O:36][CH2:37][CH3:38])=[O:39])[cH:27][cH:28]2)[cH:11][c:12](-[c:15]2[s:16][cH:17][cH:18][cH:19]2)[cH:13][cH:14]1

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 57925892Diethyl [({[4-({[2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5-(2-thienyl)phenyl]amino}carbonyl)phenyl]methyl}amino)methyl)phosphonate

Product 1

HCID 42601485Diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzylamino)methylphosphonate

Sources & evidence

ORD record
ord-d0b29e36d9d64ef093583200bb5a76b0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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