HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-3-nitrobenzyl alcohol → (3-Amino-2-methylphenyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-3-nitrobenzyl alcohol | HCID 90289 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (3-Amino-2-methylphenyl)methanol | HCID 577175 | 101.4% |
Reaction Steps
A solution of 2-methyl-3-nitrobenzyl alcohol (2.0 g, 12 mmol) in ethanol (100 ml) was hydrogenated over 10% palladium/charcoal (0.1 g) for 2 hours, at an initial pressure of 3.5 bar. The solution was filtered through celite and evaporated to give 3-amino-2-methylbenzyl alcohol (1.67 g, quantitative), m.p. 104°-106°
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05082848 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-964ca6295eb64af1ac47407e4136b9c0 |
| Source note | uspto-grants-1992_01 |