Nitric Acid → 4-(Benzyloxy)-2-nitrophenol

HRID 1090687Notes

Reaction equation

HRID 1090687 reaction equation
[C:1]1([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N+:16]([O-])([OH:18])=[O:17]>C(O)(=O)C>[N+:16]([C:11]1[CH:10]=[C:9]([O:8][CH2:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH:14]=[CH:13][C:12]=1[OH:15])([O-:18])=[O:17]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 7638Monobenzone

Product 1

HCID 46066344-(Benzyloxy)-2-nitrophenol

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

4-Phenylmethoxy-phenol in acetic acid is nitrated by contact with a slight molar excess of nitric acid at room temperature, giving 2-nitro-4-phenylmethoxy-phenol.

Workup

  1. customat room temperature

Sources & evidence

ORD record
ord-4d4659e7219844c9aeaef264dcb5cafb
Source dataset
uspto-grants-1992_01
Patent number
US05082847

Reaction notes

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