Hydrogen Peroxide → Quinoline 1-oxide

Participants

Reaction Steps

A quantity of 40 ml n-butanol, 25 ml 96% quinoline i.e. 203 mmoles and 250 mg SeO2 is introduced successively into a reactor with a capacity of 125 ml. 6 ml of 85% H2O2 are then added in 10 minutes (i.e. 200 mmoles), and the mixture is allowed to react for 2 hours at 343 K. whilst removing the water formed by azeotropic distillation. 140 mmoles of quinoline oxide are obtained in this way. The results are as follows:

Provenance & Evidence