HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 3-Pyridinesulfonic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Product | 3-Pyridinesulfonic acid | HCID 69468 | 50% |
Reaction Steps
Fischer (Ber., Vol. 15, 62 (1882) described already in 1882 the sulfonation of pyridine with concentrated sulfuric acid at 300° to 350° C. and after a reaction time of 24 hours, pyridine-3-sulfonic acid could be isolated with a yield of 50%. Subsequent investigations had the goal to produce the acid under milder reaction conditions in a shorter reaction time with a higher yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05082944 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-0cffc94d45d1426d98dcd229461c4126 |
| Source note | uspto-grants-1992_01 |