HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxygen → 2-Nitrobenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxygen | HCID 977 | — |
| Reactant | N,N-Dimethyl-2-(2-nitrophenyl)ethen-1-amine | HCID 54442712 | — |
| Catalyst | Cuprous chloride | HCID 62652 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Nitrobenzaldehyde | HCID 11101 | 88.8% |
Reaction Steps
The crude solution of β-dimethylamino-2-nitro-styrene, prepared analogously to Example 1, was diluted with 250 ml of DMF and 3 g of CuCl were added. The mixture was areated at 50° C. for 45 min. using oxygen and the solvent was then removed. After customary working-up, it was possible to isolate 88.8% of o-nitrobenzaldehyde, based on the o-nitro-toluene employed. The proportion of secondary components in the precipitated product was only 0.8%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05082976 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-71e227c3840a488398421f944556d57e |
| Source note | uspto-grants-1992_01 |