Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 3-(5-trimethylsilyl-3-furyl)propionate → 3-(2-Trimethylsilyl-4-furyl)propan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 3-(5-trimethylsilyl-3-furyl)propionate | HCID 19019871 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-(2-Trimethylsilyl-4-furyl)propan-1-ol | HCID 15037091 | — |
반응 단계
A solution of methyl 3-(2-trimethylsilyl-4-furyl)-propionate (from above) in tetrahydrofuran (3 ml) was added dropwise to a suspension of lithium aluminum hydride (27 mg) in tetrahydrofuran (4 ml) at room temperature. After 3 hours, the mixture was quenched with ethyl acetate and extracted with ether. Evaporation of the dried (magnesium sulphate) extracts gave the title alcohol, which was used in the next step without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05082954 |
| 출처 데이터셋 | uspto-grants-1992_01 |
| ORD ID | ord-8a0d85fd67334c37b9c56a6b51362e12 |
| 출처 메모 | uspto-grants-1992_01 |