HCID 14478189, compound → HCID 86745418, compound

HRID 1090954Notes

Reaction equation

HRID 1090954 reaction equation
[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[C:7](O)(=O)[C:8](O)=O.CN(CCC1C=CC=C(C)N=1)CCC([C:19]1[CH:24]=[CH:23][C:22]([NH:25][S:26]([CH3:29])(=[O:28])=[O:27])=[CH:21][CH:20]=1)=O.C(O)(=O)C(O)=O.C(O)(=O)C(O)=O.[CH2:51]([N:53]([CH2:70][CH2:71][C:72]1[CH:77]=[CH:76][CH:75]=C(C)[N:73]=1)CCCC(C1C=CC(NS(C)(=O)=O)=CC=1)=O)C.C(O)(=O)C(O)=O.C(O)(=O)C(O)=O.CS(N)(=O)=O>>[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH3:51][N:53]([CH2:70][CH2:71][C:72]1[CH:77]=[CH:76][CH:75]=[C:7]([CH3:8])[N:73]=1)[C:19]1[CH:20]=[CH:21][C:22]([NH:25][S:26]([CH3:29])(=[O:27])=[O:28])=[C:23]([C:1](=[O:6])[CH3:2])[CH:24]=1

Participants

4

Reactant 3

HCID 14478189HCID 14478189, compoundHCID 14478193HCID 14478193, compoundHCID 86745419HCID 86745419, compound

Product 1

HCID 86745418HCID 86745418, compound

Procedure

##STR27## Compound B: Compound prepared in Example 2: N-[4-[3-{N-methyl-(6-methyl-2-pyridyl)-ethylamino}propionyl]phenyl]methanesulfonamide dioxalate: ##STR28## Compound C; Compound prepared in Example 4: N-[4-[4-{N-methyl-2-(6-methyl-2-pyridyl)-ethylamino}butyrul]phenyl]methanesulfonamide dioxalate: ##STR29## Compound D: Compound prepared in Example 5: N-[4-[4-{N-ethyl-2-(6-methyl-2-pyridyl)-ethylamino}butyryl]phenyl]methanesulfonamide dioxalate: ##STR30## Compound E: Compound prepared in Example 6: N-[4-[5-{6-methyl-2-pyridyl)ethylamino}valeryl]-phenyl]methanesulfonamide dioxalate: ##STR31##

Sources & evidence

ORD record
ord-44e26ccf3ce343fdbe8b8b169b529cba
Source dataset
uspto-grants-1992_01
Patent number
US05082850

Reaction notes

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