Sodium Hydroxide → HCID 22419198, compound

HRID 1090958Notes

Reaction equation

HRID 1090958 reaction equation
S(S([O-])=O)([O-])=O.[Na+].[Na+].[Cl:9][C:10]1[C:15]([OH:16])=[CH:14][C:13]([O:17][CH2:18][CH2:19][OH:20])=[C:12]([N+:21]([O-])=O)[CH:11]=1.[OH-].[Na+]>O>[ClH:9].[NH2:21][C:12]1[CH:11]=[C:10]([Cl:9])[C:15]([OH:16])=[CH:14][C:13]=1[O:17][CH2:18][CH2:19][OH:20]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 24489Sodium DithioniteHCID 22419194HCID 22419194, compound

Product 1

HCID 22419198HCID 22419198, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

70 g of sodium hydrosulphite are added portionwise and with stirring to a solution of 32 g of 6-chloro-3-(β-hydroxyethoxy)-4-nitrophenol phenate and 75 ml of 10 N NaOH in 250 ml of water, the temperature being maintained in the region of 60°-65° C. After the mixture is cooled, the product is precipitated by neutralizing the reaction medium with acetic acid. The hydrochloride is obtained by dissolution in hydrochloric acid in the heated state and precipitation on cooling.

Workup

  1. temperaturethe temperature being maintained in the region of 60°-65° C
  2. temperatureAfter the mixture is cooled
  3. customthe product is precipitated

Sources & evidence

ORD record
ord-e900e1c1d5e047aeaeb7dd76a224db72
Source dataset
uspto-grants-1992_01
Patent number
US05084067

Reaction notes

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