HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylbenzoyl isothiocyanate → N-[[[2-(Aminocarbonyl)-4-methylphenyl]amino]thioxomethyl]-4-methylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylbenzoyl isothiocyanate | HCID 140139 | — |
| Reactant | 2-Amino-5-methylbenzamide | HCID 10329436 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | N-[[[2-(Aminocarbonyl)-4-methylphenyl]amino]thioxomethyl]-4-methylbenzamide | HCID 15135527 | 91.7% |
Reaction Steps
To a stirred mixture of 3 g of 2-amino-5-methylbenzamide and 200 ml of ether was added dropwise, a solution of 3.7 g of 4-methylbenzoyl isothiocyanate in 100 ml of ether over 30 minutes. After 24 hours the solid was collected, giving 6 g of N-[[[2-(aminocarbonyl)-4-methylphenyl]amino]thioxomethyl]-4-methylbenzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05084457 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-a5e014f79893459ab69006a2b1d81400 |
| Source note | uspto-grants-1992_01 |