HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 1,1-Ethenediamine, N-[(6-chloro-3-pyridinyl)methyl]-N'-methyl-2-nitro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-(6-Chloro-3-pyridylmethyl)amino-1-methylthio-2-nitroethylene | HCID 85592932 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1,1-Ethenediamine, N-[(6-chloro-3-pyridinyl)methyl]-N'-methyl-2-nitro- | HCID 4325619 | 92.6% |
Reaction Steps
A mixture of 2.0 g of 1-(6-chloro-3-pyridylmethylamino)-1-methylthio-2-nitroethylene, 1.8 g of 40% aqueous methylamine solution and 20 ml of acetonitrile was refluxed for 3 hours and, then concentrated. The residue was washed with dichloromethane to give 1.73 g of 1-(6-chloro-3-pyridylmethylamino)-1-methylamino-2-nitroethylene. Mp 181°-183° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05084459 |
| Source dataset | uspto-grants-1992_01 |
| ORD ID | ord-fb82296495ff4b458910120aaefba1b0 |
| Source note | uspto-grants-1992_01 |