反应详情

Dissolve 12,12,12-trifluoro-8-dodecenoic acid (1.39 g, 5.5 mmol) in ethanol (50 mL) and place in a Paar hydrogenation flask. Add 10% palladium/carbon (500 mg). Charge the vessel to 50 psi and shake for 18 hours. Filter through celite and remove the solvent in vacuo to give 12,12,12-trifluorododecanoic acid.

1. additionCharge the vessel to 50 psi
2. filtrationFilter through celite
3. customremove the solvent in vacuo