HCID 53672027, compound → 12,12,12-trifluorododecanoic Acid

HRID 1091069Notes

Reaction equation

HRID 1091069 reaction equation
[F:1][C:2]([F:17])([F:16])[CH2:3][CH2:4][CH:5]=[CH:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14]>C(O)C.[Pd]>[F:1][C:2]([F:16])([F:17])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14]

Participants

4

Reactant 1

HCID 53672027HCID 53672027, compound

Product 1

HCID 981373812,12,12-trifluorododecanoic Acid

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Dissolve 12,12,12-trifluoro-8-dodecenoic acid (1.39 g, 5.5 mmol) in ethanol (50 mL) and place in a Paar hydrogenation flask. Add 10% palladium/carbon (500 mg). Charge the vessel to 50 psi and shake for 18 hours. Filter through celite and remove the solvent in vacuo to give 12,12,12-trifluorododecanoic acid.

Workup

  1. additionCharge the vessel to 50 psi
  2. filtrationFilter through celite
  3. customremove the solvent in vacuo

Sources & evidence

ORD record
ord-eff658b46e1948b8a756cfcfb15a00b1
Source dataset
uspto-grants-1992_01
Patent number
US05084461

Reaction notes

Loading…