Mannitol → HCID 178418489, compound

HRID 1091206Notes

Reaction equation

HRID 1091206 reaction equation
[CH2:1]([OH:12])[C@H:2]([C@H:4]([C@@H:6]([C@@H:8](CO)[OH:9])[OH:7])[OH:5])[OH:3]>O.C(O)C>[CH2:1]([OH:12])[C@@H:2]([C@H:4]([C@@H:6]([CH2:8][OH:9])[OH:7])[OH:5])[OH:3]

Participants

4

Reactant 1

HCID 6251Mannitol

Product 1

HCID 178418489HCID 178418489, compoundYield 119.7%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

The procedure of Example 1 was repeated except that 300 mg of mannitol was dissolved in a mixture of 10 mg of water and 10 mg of ethanol, the solution was subjected to wet granulation, and the resulting wet granules were dried and used as the sugar alcohol, not 300 mg of xylitol, to obtain an inventive rapidly disintegrating formulation tablet.

Workup

  1. customthe resulting wet granules were dried

Sources & evidence

ORD record
ord-9b6ecdf8dfcc434aa8562bd50920dea3
Source dataset
uspto-grants-2012_03
Patent number
US08127516B2

Reaction notes

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