化工社化工社 化学情報印刷レポート · 研究参考用
Water → 4-Morpholino-2-nitrobenzonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Morpholine | HCID 8083 | — |
| 反応物 | 2,4-Dinitrobenzonitrile | HCID 554082 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4-Morpholino-2-nitrobenzonitrile | HCID 13499265 | 82.8% |
反応手順
A mixture of 2,4-dinitrobenzonitrile 4.20 g (21.75 mmol) and morpholine 5.7 mL (66.0 mmol) in N,N-dimethylformamide 20 mL was stirred at room temperature for 20 hours. The reaction mixture was poured into water. The precipitate was collected and washed with water to give the title compound 4.20 g as orange solid. Yield 74.5%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08129386B2 |
| 出典データセット | uspto-grants-2012_03 |
| ORD ID | ord-02cebe0ec2ed4d2abe6ec47f4a5a4591 |
| 出典メモ | uspto-grants-2012_03 |