2-(4-chloro-5-methyl-1H-pyrazol-3-yl)pyridine → 1-[4-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-methylpiperazin-1-yl]-2-(4-chloro-5-methyl-3-pyridin-2-ylpyrazol-1-yl)ethanone

HRID 109157Notes

Reaction equation

HRID 109157 reaction equation
[Cl:1][CH2:2][C:3](=[O:4])[N:5]1[CH:6]([CH3:21])[CH2:7][N:8]([c:11]2[c:12]([F:20])[cH:13][c:14]([Cl:19])[c:15]([O:17][CH3:18])[cH:16]2)[CH2:9][CH2:10]1.[Cl:22][c:23]1[c:24](-[c:29]2[n:30][cH:31][cH:32][cH:33][cH:34]2)[n:25][nH:26][c:27]1[CH3:28]>>[CH2:2]([C:3](=[O:4])[N:5]1[CH:6]([CH3:21])[CH2:7][N:8]([c:11]2[c:12]([F:20])[cH:13][c:14]([Cl:19])[c:15]([O:17][CH3:18])[cH:16]2)[CH2:9][CH2:10]1)[n:26]1[n:25][c:24](-[c:29]2[n:30][cH:31][cH:32][cH:33][cH:34]2)[c:23]([Cl:22])[c:27]1[CH3:28]

Participants

3

Reactant 2

HCID 578402932-(4-chloro-5-methyl-1H-pyrazol-3-yl)pyridineHCID 671040732-Chloro-1-[4-(4-chloro-2-fluoro-5-methoxy-phenyl)-2-methyl-piperazin-1-yl]-ethanone

Product 1

HCID 688190691-[4-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-methylpiperazin-1-yl]-2-(4-chloro-5-methyl-3-pyridin-2-ylpyrazol-1-yl)ethanone

Sources & evidence

ORD record
ord-19ca652bbd3c4c6fa83b2c05a6e75c2a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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