反应详情

2-(Benzothiazol-2-yl)acetonitrile (2.05 g, 12 mmol) was added in portions to stirred concentrated sulfuric acid (5 mL) over 10 min. The mixture was stirred for 4 hr, then poured over ice/water. The precipitate that formed was extracted into EA and washed with brine, then the organic phase was dried over magnesium sulfate and the solvent removed under vacuum to give 2-(benzothiazol-2-yl)acetamide (1.02 g) as an orange solid.

1. customThe precipitate that formed
2. extractionwas extracted into EA
3. washwashed with brine
4. dry with materialthe organic phase was dried over magnesium sulfate
5. customthe solvent removed under vacuum