5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine → 5-{1-[6-Cyclopropyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-1H-imidazol-4-yl}-pyridin-2-ylamine
Reaction equation
[CH:1]1([c:4]2[n:5][c:6](-[n:20]3[cH:21][n:22][c:23]([I:25])[cH:24]3)[cH:7][c:8](-[c:10]3[cH:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]3)[cH:9]2)[CH2:2][CH2:3]1.[NH2:26][c:27]1[n:28][cH:29][c:30]([B:33]2[O:34][C:35]([CH3:36])([CH3:37])[C:38]([CH3:39])([CH3:40])[O:41]2)[cH:31][cH:32]1>>[CH:1]1([c:4]2[n:5][c:6](-[n:20]3[cH:21][n:22][c:23](-[c:30]4[cH:29][n:28][c:27]([NH2:26])[cH:32][cH:31]4)[cH:24]3)[cH:7][c:8](-[c:10]3[cH:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]3)[cH:9]2)[CH2:2][CH2:3]1Participants
3
Sources & evidence
- ORD record
- ord-0aab3903a1144d46b2807782c6e4f7fc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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