Hydrochloric Acid → HCID 11669130, compound

Participants

Reaction Steps

N-(3,5-dichloropyridin-4-yl)-2-(tert-butoxycarbonyl)-8-methoxy-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridine-5-carboxamide (from step 3) (645 mg, 0.0013 mol) was taken in dry ethyl acetate and ethyl acetate saturated with HCl was added to it at 0° C. it was then stirred for an hour. Ethyl acetate was removed under diminished pressure and dry solvent ether was added to it. Solid N-(3,5-dichloropyridin-4-yl)-8-methoxy-1,2,3,4-tetrahydro[1]benzofuro[2,3-c]pyridine-5-carboxamide hydrochloride (XIII) was filtered, washed with dry solvent ether and dried.

Provenance & Evidence