HCID 57531479, compound → HCID 57531423, compound

Participants

Reaction Steps

To a solution of 2-(4-(2-(2,6-diethylphenyl)-5-((5-isopropyl-2-methylphenoxy)methyl)-6-methylpyrimidin-4-yl)-5,6-dihydropyridin-1(2H)-yl)acetamide (131 mg, 0.25 mmol) in EtOAc (5 mL) is added 5% Pd/C (100 mg). The mixture is hydrogenated at room temperature and atmosphere pressure for 16 h. After filtered though celite, the solution is concentrated and purified by silica gel column chromatography to provide the title product. [mass expected (528.7); mass found (M+1: 529.4)].

Provenance & Evidence