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3,5-Pyridinedicarboxylic acid (1.5 g, 63 mmol) and conc. H2SO4 (0.9 mL) in MeOH (15 mL) are heated in a microwave oven at 120° C. for 2 h. The solvent is evaporated to give a residue with is partitioned between ethyl acetate and sat. aq. NaHCO3. The organic phase is washed with brine, dried over Na2SO4, filtered and evaporated to give a light yellow solid. MS (LC-MS): 196 [M+H]+ TLC, Rf (ethyl acetate/hexane 1:1)=0.56.

1. customThe solvent is evaporated
2. customto give a residue
3. customwith is partitioned between ethyl acetate and sat. aq. NaHCO3
4. washThe organic phase is washed with brine
5. dry with materialdried over Na2SO4
6. filtrationfiltered
7. customevaporated
8. customto give a light yellow solid