Methyl iodide → HCID 24965504, compound

HRID 1092319Notes

Reaction equation

HRID 1092319 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[N:11]1[CH:15]=[C:14]([CH:16]3[CH2:18][CH2:17]3)[NH:13][C:12]1=[O:19])[CH2:8]2.I[CH3:21]>>[CH:1]12[CH2:8][CH:7]3[CH2:6][CH:5]([CH2:4][CH:3]([CH2:9]3)[CH:2]1[N:11]1[CH:15]=[C:14]([CH:16]3[CH2:17][CH2:18]3)[N:13]([CH3:21])[C:12]1=[O:19])[CH2:10]2

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 24964792HCID 24964792, compound

Product 1

HCID 24965504HCID 24965504, compound

Procedure

This material was obtained in analogy to the procedure outlined in example 23 from 1-adamantan-2-yl-4-cyclopropyl-1,3-dihydro-imidazol-2-one (obtained in example 15, 100 mg) by alkylation with iodomethane (82 mg). 1-Adamantan-2-yl-4-cyclopropyl-3-methyl-1,3-dihydro-imidazol-2-one was obtained as a light yellow oil (52 mg). MS (EI): 272.3 (M+).

Workup

  1. customThis material was obtained in analogy to the procedure

Sources & evidence

ORD record
ord-1102bc0c17b64c788920b330b9580710
Source dataset
uspto-grants-2012_03
Patent number
US08129423B2

Reaction notes

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