HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 24966557, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 24966556 | HCID 24966556 | — |
| Solvent | Heptane | HCID 8900 | — |
| Product | HCID 24966557 | HCID 24966557 | — |
| Product | HCID 24966558 | HCID 24966558 | — |
Reaction Steps
Racemic 1-adamantan-2-yl-4-isopropyl-imidazolidin-2-one (320 mg, example 51) was subjected to preparative HPLC (Column: Chiralpack AD; Eluent: 15% ethanol in heptane; Flow: 35 mL/min; Detection: UV 220 nm) to give (R)-1-adamantan-2-yl-4-isopropyl-imidazolidin-2-one (136 mg, tRet=45 min) and (S)-1-adamantan-2-yl-4-isopropyl-imidazolidin-2-one (115 mg, tRet=64 min). Absolute configurations are tentatively assigned.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08129423B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-459f8c16d7764bdb9d2bb8d7f476d80f |
| Source note | uspto-grants-2012_03 |