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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1092380Generated: November 1, 2026

Dimethylamine → HCID 59596854, compound

https://huagongshe.com/reaction/1092380

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
ReactantTrimethylaluminumHCID 16682925—
ReactantHCID 59596844HCID 59596844—
SolventTetrahydrofuranHCID 8028—
SolventHeptaneHCID 8900—
ProductHCID 59596854HCID 5959685452%

Reaction Steps

This compound was synthesized according to the procedure described in Scheme 6, step B, using 115 mg of 2-[2-[4-(3-fluoro-benzyloxy)-3-methoxy-phenyl]-ethylamino]-2-phenyl-acetic acid methyl ester (0.27 mmol), 1.06 ml (2.1 mmol) of a 2 M solution of dimethylamine in tetrahydrofuran and 0.53 ml (1.06 mmol) of a 2 M solution of trimethyl aluminium in heptane. 66 mg (52% yield) of the title compound were isolated as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08129427B2
Source datasetuspto-grants-2012_03
ORD IDord-f41ec9b08c4644c5b76b05cf51bd0e39
Source noteuspto-grants-2012_03