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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 109252Generated: October 26, 2026

Dimethyl Sulfoxide → 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-[2-(hydroxymethyl)pyrrolidin-1-yl]pyridin-3-yl]-N,2-dimethylpropanamide

https://huagongshe.com/reaction/109252

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantCarbonate IonHCID 19660—
ReactantProlinolHCID 90908—
Reactant2-(3,5-Bis(trifluoromethyl)phenyl)-N-(6-chloro-4-(4-fluoro-2-methylphenyl)pyrid-3-yl)-N,2-dimethylpropanamideHCID 23502784—
Product2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-[2-(hydroxymethyl)pyrrolidin-1-yl]pyridin-3-yl]-N,2-dimethylpropanamideHCID 78073999—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-3744246fdb9a440ea91476a4e7f8e449
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)