Hydrogen Bromide → HCID 66588743, compound

Participants

Reaction Conditions

Reaction Steps

Intermediate II (19 mg) was placed in a microwave reactor vial and 48% HBr was added. The vial was sealed with a septum, and mixture was stirred at 160° C. for 0.5 h under microwave irradiation. The crude mixture was concentrated in vacuo, and the residue was purified by preparative LC/MS. Yield of example 2a1: 12.6 mg as a white solid. LC/MS (method 17): RT 1.48 min, ELSD 95.9%, UV 87.1%. MH+: 220.1.

Provenance & Evidence