Trifluoroacetic acid methylene chloride → HCID 56849388, compound

Participants

Reaction Steps

Into a 10 mL round bottom flask was added 19D (50 mg, 79 μmol) and 25% TFA/DCM (5 mL). The mixture was stirred at room temperature for 3 hours. Solvent was removed under vacuum and the residue was purified by preparatory LCMS to yield Compound 14 (25-80%). 1H NMR (400 MHz, DMSO-d6) δ ppm 0.23-0.91 (m, 4H) 2.33 (m, 2H) 2.99 (br. s., 1H) 3.30-3.59 (m, 4H) 4.07-4.68 (m, 7H) 6.85-7.07 (m, 2H) 7.14-7.31 (m, 4H) 7.40-7.59 (m, 4H). ESI-MS:m/z 636.2 (M+H)+.

Provenance & Evidence