HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → HCID 85861728, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | 1-(p-Methoxyphenyl)-2-propanone | HCID 31231 | — |
| Reactant | Acetylthiourea | HCID 2723593 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 85861728 | HCID 85861728 | — |
Reaction Steps
4-methoxyphenylacetone (10 g, 60.9 mmol), N-acetylthiourea (7.2 g, 60.9 mmol) and iodine (15.46 g, 60.9 mmol) in pyridine (50 ml) are stirred at 70° C. for 16 hours. The mixture is concentrated and the residue is purified by chromatography on silica with iso-hexane-ethyl acetate (1:1) to give the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08129541B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-aa6f84a0093c4743a082c487ad58035c |
| Source note | uspto-grants-2012_03 |