Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetylthiourea | HCID 2723593 | — |
| Reactant | HCID 85861651 | HCID 85861651 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 85861692 | HCID 85861692 | — |
Reaction Steps
1-Bromo-1-(4-fluoro-3-methoxy-phenyl)-propan-2-one (161b) (0.72 g, 2.74 mmol) is dissolved in ethanol (20 ml) and N-acetylthiourea (0.324 g, 2.72 mmol) is added in one portion. The mixture is stirred at 80° C. overnight then allowed to cool whereupon the product crystallised. Filtration affords the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08129541B2 |
|---|
| Source dataset | uspto-grants-2012_03 |
|---|
| ORD ID | ord-24864d18095f4ee39d4e2ae1162b3bb8 |
|---|
| Source note | uspto-grants-2012_03 |
|---|
