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HRID1092999

反应详情

EQUATION

反应方程式

HRID 1092999 的结构方程式

REACTANTS

反应物

3
结构：CCOC(=O)CCN=C=O
HCID2733373

ethyl 3-isocyanatopropanoate

C6H9NO3

结构：Cc1nc(N)sc1-c1ccc(S(C)(=O)=O)c(C(F)(F)F)c1
HCID57473749

未命名化合物

结构：CCOC(=O)CCCNC(=O)Nc1nc(C)c(-c2ccc(S(C)(=O)=O)c(F)c2)s1
HCID86598431

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)CCNC(=O)Nc1nc(C)c(-c2ccc(S(C)(=O)=O)c(C(F)(F)F)c2)s1
HCID86598433

未命名化合物

PROCEDURE

实验过程

The title compound is prepared by the same procedure as 4-{3-[5-(3-fluoro-4-methanesulfonyl-phenyl)-4-methyl-thiazol-2-yl]-ureido}-butyric acid ethyl ester (Example 164) by replacing 5-(3-fluoro-4-methanesulfonyl-phenyl)-4-methyl-thiazol-2-ylamine (Example 72) with 5-(4-methanesulfonyl-3-trifluoromethyl-phenyl)-4-methyl-thiazol-2-ylamine (158a) and replacing ethyl-4-isocyanatobutyrate with 3-isocyanato-propionic acid ethyl ester.