Ethyl 4-methyl-2-(2-oxo-3-phenylimidazolidin-1-yl)thiazole-5-carboxylate → 4-Methyl-2-(2-oxo-3-(4-(trifluoromethoxy)benzyl)imidazolidin-1-yl)thiazole-5-carboxylic acid
Reaction equation
[CH3:1][c:2]1[n:3][c:4]([N:5]2[CH2:6][CH2:7][N:8]([c:9]3[cH:10][cH:11][cH:12][cH:13][cH:14]3)[C:15]2=[O:16])[s:17][c:18]1[C:19]([O:20][CH2:21][CH3:22])=[O:23].[CH3:24][c:25]1[n:26][c:27]([N:35]2[C:36](=[O:52])[N:37]([CH2:40][c:41]3[cH:42][cH:43][c:44]([O:47][C:48]([F:49])([F:50])[F:51])[cH:45][cH:46]3)[CH2:38][CH2:39]2)[s:28][c:29]1[C:30](=[O:31])[O:32][CH2:33][CH3:34]>>[CH3:24][c:25]1[n:26][c:27]([N:35]2[C:36](=[O:52])[N:37]([CH2:40][c:41]3[cH:42][cH:43][c:44]([O:47][C:48]([F:49])([F:50])[F:51])[cH:45][cH:46]3)[CH2:38][CH2:39]2)[s:28][c:29]1[C:30](=[O:31])[OH:32]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c6e0915ec42b44e1861d5f66dfd1e29e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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