HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloride → HCID 57424393, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloride | HCID 312 | — |
| Reactant | HCID 66589044 | HCID 66589044 | — |
| Reactant | HCID 75080609 | HCID 75080609 | — |
| Product | HCID 57424393 | HCID 57424393 | — |
Reaction Steps
A Suzuki coupling procedure similar to that used for the synthesis of ethyl 4-(6-(4-aminophenyl)-4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate is used, using methyl 4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-chloro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate as the chloride component (68%, MS=464.2 (M+H))
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08129371B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-ca047e432b8b45779a3cfdd6cb491ae3 |
| Source note | uspto-grants-2012_03 |