HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbamate → HCID 66589145, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbamate | HCID 276 | — |
| Reactant | Propylene Glycol | HCID 1030 | — |
| Reactant | ethyl 4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(4-(3-ethylureido)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate | HCID 25262323 | — |
| Product | HCID 66589145 | HCID 66589145 | — |
Reaction Steps
A carbamate formation procedure similar to that used for the synthesis of ethyl 4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(4-(3-ethylureido)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate is used, utilizing 1,2-propanediol as the alcohol component. (24%, MS=453.2 (M+H))
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08129371B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-e5d517b75e16460a8637f624c9267861 |
| Source note | uspto-grants-2012_03 |