Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Bromo-4-phenylbutane | HCID 259668 | — |
| Reactant | HCID 57704536 | HCID 57704536 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 59407590 | HCID 59407590 | 103.8% |
Reaction Steps
Compound 3-6 (350 mg) was dissolved in N,N-dimethylformamide (10 ml), potassium carbonate (255 mg) and 4-phenylbutylbromide (235 mg) were added, and the mixture was stirred at 80° C. for 6 hr. Water was added to the reaction mixture, and the mixture was extracted with ethyl acetate, washed with water and saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give the object product (490 mg) as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08129361B2 |
|---|
| Source dataset | uspto-grants-2012_03 |
|---|
| ORD ID | ord-0d7f18c9478f4e07b4822a913659d184 |
|---|
| Source note | uspto-grants-2012_03 |
|---|
